Nutrition for Women
100% Natural
Cold Processed

Dietary Supplement

100 Softgels

DOCTOR RECOMMENDED

More Info:
Laboratory Tested To Guarantee Quality
For Health Care Professional Use Only

HOW PATIENTS MAY BENEFIT
Helps provide nutritional support to women with PMS

PRODUCT DISCUSSION
PhysioLogics Evening Primrose Oil (EPO) supplies 45 mg of Gamma-Linolenic Acid (GLA) per softgel and up to 270 mg per day to help provide nutritional support for overall health and for women with PMS. GLA is an omega-6 fatty acid that can be synthesized from Linoleic Acid in the body by the rate-limiting enzyme delta-6 desaturase. However, biological conversion is estimated to be less than 10% and is affected by several factors, including aging; intake of certain nutrients such as zinc, B6, magnesium, biotin and calcium; stress; and cholesterol levels. GLA does not have significant food sources, so supplementation may be important.

STRUCTURE AND FUNCTION
GLA promotes cellular and metabolic health. It is a precursor to prostaglandins, action-specific bio-molecules that regulate many important functions in cells, and provides nutritional support for women with PMS by modulating prostaglandin production. GLA also supports the immune system and can help with dry skin.

CLINICAL EVIDENCE
Fourteen (14) subjects were assessed for effects on skin health after receiving capsules of evening primrose oil containing 40 mg of gamma linolenic acid (GLA) per capsule twice per day. All subjects reported improvements in skin health, with 42.8% subjects having complete improvement in skin health. (Yoon et al, 2002) In a preliminary clinical trial with 68 women who had a history of PMS, 500 mg of EPO taken twice daily led to an overall positive effect on PMS scores, which were based on mood, mental well-being, comfort, and fluid retention. Over 60% of the women who had poor success with PMS previously had a reported "good" response to EPO when compared to placebo. (Brush et al, 1984)

SUMMARY
PhysioLogics Evening Primrose Oil is a source of Gamma-Linolenic Acid and provides nutritional support for overall health and for women with PMS.

PRODUCT BENEFITS:
Evening Primrose Oil is one of nature's most abundant sources of the important unsaturated fatty acid, Gamma-Linolenic Acid (GLA). Gamma-Linolenic Acid is a precursor to prostaglandins, action-specific biomolecules that regulate many important functions in cells. This product is 100% solvent free, cold-processed, and is void of Hexane and all other solvent residue.

Ingredients:
Serving Size: 1 Softgel

Amount Per Serving
Calories ...5
Calories from Fat ...5
Total Fat ...0.5g / 1% DV**
Evening Primrose Oil (seed) ...500mg***
Cis-Linoleic Acid (LA) ...365mg***
Gamma-Linolenic Acid (GLA) ...45mg***

**Percent Daily Values are based on a 2,000 calorie diet.
***Daily Value not established.

Other Ingredients: Gelatin, Glycerin.

FREE OF: artificial color, flavor or sweetener, preservatives, sugar, starch, milk, lactose, soy, gluten, wheat, yeast, fish, sodium.

Dosage:
Directions:
For adults, take one (1) softgel three (3) to six (6) times daily, preferably with meals or follow the advice of your health care professional. As a reminder, discuss the supplements and medications you take with your health care providers.

WARNINGS:
TAMPER RESISTANT:
Do not use if seal under cap is broken or missing.

KEEP OUT OF REACH OF CHILDREN.

Store in a dry place and avoid excessive heat.

WARNING:
If you are pregnant, nursing or taking any medications, consult your doctor before use.