Nutritional Support
for Bone Health

Dietary Supplement

90 Vegetarian Caplets

DOCTOR RECOMMENDED

More Info:
Laboratory Tested To Guarantee Quality
For Health Care Professional Use Only

PRODUCT IS A MIXTURE OF
Calcium Citrate, Calcium Carbonate, Calcium Stearate, Magnesium Citrate, Magnesium Glycinate.

PRODUCT DISCUSSION
Calcium is the major mineral responsible for the health of the body's bones and teeth. Calcium intake is critical to achieving peak bone mass, maintaining muscle contractions, nerve impulses and supporting heart health. This unique formula contains Calcium Citrate, one of the most bioavailable sources of Calcium, with chelated Magnesium for additional support of bone health.

STRUCTURE AND FUNCTION
Calcium is an essential nutrient compromising 2% of adult body weight. More than 99% of the body's Calcium is found in the skeleton, representing 25% of the dry weight of bones. Calcium reacts with phosphoric acid to form insoluble salts whose primary function is to provide rigidity to the skeleton. In addition, the Calcium salts are required to maintain a critical Calcium concentration in extra-cellular water, which is necessary for support of the heart, neuromuscular system, and enzymatic reactions.

Bone is a dynamic tissue, going through a continuous process of formation and absorption. Calcium accumulates in the skeleton during childhood until maturity when equilibrium is reached. During midlife the body acquires the Calcium it needs by slowly absorbing bone. Adequate Calcium intake during adolescence and adulthood is crucial to achieve optimal bone mass.

Many factors contribute to the development of osteoporosis including sex, race, age, and hormonal status. Even your body type, family history, Calcium intake, and how often you exercise can have an impact. Some populations, especially Caucasian women of northern European ancestry and Asian women in their bone forming years (teens and young adults) have a higher risk of developing osteoporosis. Women going through menopause, those with a family history of the disease and the elderly are also at a higher risk. American women of African heritage have the lowest incidence of osteoporotic fracture.

It's important to remember that everyone loses bone mass with age. Regular exercise, a healthy diet and adequate Calcium intake helps maintain good bone health and may reduce the high risk of osteoporosis later in life, especially for teens and young adult Caucasian and Asian women. A total dietary intake above 2,000 mg has no further known benefit to bone health.

Magnesium also plays an important role in bone health. The human skeleton utilizes 55% of the body's Magnesium. Magnesium aids in the absorption of Calcium by promoting the secretion of calcitonin, a hormone that aids in the influx of calcium into bone. In addition, Magnesium modulates the secretion of parathyroid hormone, whose function is to draw Calcium out of bones and deposit it in soft tissue.

INDICATIONS
Adequate Calcium intake during adolescence, adulthood and menopause is crucial to achieve and maintain peak bone mass. According to the Third National Health and Nutrition Examination Survey (NHANES III), more than 50% of children, adults, and elderly Americans' dietary Calcium intakes fail to meet recommended levels. In addition, certain regularly prescribed drugs may cause Calcium and/or Magnesium depletions. PhysioLogics' Calsorb® may be a desirable dietary supplement for clients who want to promote bone mass and support overall bone health.

HOW CLIENTS MAY BENEFIT
Primary support of bone health begins during adolescence when the skeleton is accruing its peak mass. The Food and Nutrition Board of the Institute of Medicine issued a Dietary Reference Intake for Calcium to 1,300 mg per day for 9 to 18 year old girls, and 1000 mg for 19 to 50 year old women. Calcium supplementation during these formative years may contribute to bone density in the future.

Optimize peak bone mass during all stages of life for a strong skeletal system in both men and women.

Provide extra Calcium normally obtained from bones required for proper muscle contraction and nerve function.

Magnesium aids in the absorption of Calcium into bone and is essential to maintain proper bone mineralization.

NIAMS, a branch of the National Institutes of Health, recently completed a placebo-controlled double blind study evaluating the effect of Calcium supplementation on bone mass accretion over 7 years in a group of 354 prepubescent females. The results will provide data about the efficacy of Calcium supplementation with regard to bone mass, circulatory health, and weight control.

A study of 12 young healthy men found that daily supplementation with 15 mmol (365mg) Magnesium supports bone health, as measured by reduced levels of resorption biochemical markers.

CLINICAL EVIDENCE
A French study shows that Calcium and Vitamin D supplementation may not only promote bone health, but may also increase bone mass. Over 3,000 women over the age of 69 received 1.2 grams of calcium and 800 IU of Vitamin D or a placebo every day for 18 months. Not only did 43% of the supplemented women have stronger bones, but bone density increased slightly in this group as well. A meta-analysis of four well-designed intervention studies concludes that Calcium supplementation of ~1000 mg/d in women can promote bone health in every bone except the ulna. A placebo-controlled double-blind study of 389 men and women over 65 years old found a significant positive change in bone density in patients that consumed 500 mg Calcium and 700 IU Vitamin D for 3 years versus the placebo group.

SUMMARY
Calcium and Magnesium are essential nutrients for bone formation and maintenance. PhysioLogics' Calsorb® combines Calcium and Magnesium in a highly absorbable form for those who want to ensure they obtain adequate amounts of these minerals to support bone health through all stages of life.

PRODUCT BENEFITS:
Calcium is the major mineral responsible for the health of the body’s bones and teeth. Calcium intake is critical to achieving peak bone mass. Calcium also helps maintain muscle contractions, nerve impulses and heart health. This unique formula contains calcium citrate - one of the most bioavailable sources of calcium - with chelated magnesium to balance the intake of calcium.

Ingredients:
Serving Size: 3 Caplets
Servings Per Container: 30

Amount Per Serving
Calcium ...503mg / 50% DV
(as 80% Calcium Citrate, 20% Calcium Carbonate, Calcium Stearate)
Magnesium ...250mg / 63% DV
(as 50% Magnesium Citrate, 50% Magnesium Glycinate)

Other Ingredients: Cellulose (Plant Origin), Croscarmellose, Silica, Cellulose Coating.

FREE OF: yeast, wheat, milk or milk derivatives, lactose, preservatives, soy, artificial color, artificial flavor.

Dosage:
Directions: For adults, take three (3) caplets one to two times per day preferably with a meal or follow the advice of your health care professional. As a reminder, discuss the supplements and medications you take with your health care providers.

WARNINGS:
TAMPER RESISTANT:
Do not use if seal under cap is broken or missing.

KEEP OUT OF REACH OF CHILDREN.

Store in a dry place and avoid excessive heat.