RECOMMENDED TO ENHANCE STRUCTURE & FUNCTION RELATING TO NUTRITIONAL
NEEDS AND DEFICIENCIES PERTAINING TO:
∑ Defending the body against free radical damage
∑ Detoxifying toxic compounds in the liver and lungs
∑ Enhancing immune system and having anticarcinogenic properties
∑ Helping to protect against atherosclerosis
∑ Glutathione deficiencies, which can lead to serious health problems
∑ Aging, which are associated with low Glutathione levels.
∑ Protection from virus infection, cornea injuries, metal intoxication, etc.
WHAT IS GLUTATHIONE?
Glutathione (Glutathione Reduced) is a tripeptide made from the amino acids Cysteine, Glutamic acid and
Glycine. Vitamin B-6 is necessary for proper metabolism and Alpha Lipoic Acid helps increase Glutathione
levels. Vitamins C and E, and also Selenium have an effect on Glutathione levels. Produced in the liver,
which has the most abundant supply, this powerful antioxidant helps detoxify harmful chemical compounds.
Found in almost every cell of the body, Glutathione protects against free radical damage. Glutathione levels
decrease with aging, especially after the age 40. Low levels accelerate the aging process, and have been
associated with disease and premature death; therefore, it is very important to keep these levels high.
Glutathione is the cellís primary antioxidant, found in the cell sap, and is necessary to protect the cells from
free radical damage, which causes aging and severe health problems. It works synergistically with Vitamin E,
Vitamin C, Alpha Lipoic Acid, and Co-Q 10 to provide a powerful defensive mechanism. There are very high
levels found in the liver, which detoxifies drugs, pollutants, and other harmful substances. Smoking
cigarettes, excessive intake of alcohol, eating highly processed foods that contain nitrates, and drugs (such
as acetaminophen) can deplete the body of important Glutathione. There have been health warnings not to
take acetaminophen if you consume alcohol. Both of these generate free radicals and this can deplete the
liver of Glutathione. If the liver is depleted of Glutathione, it cannot function properly and it builds up with
excessive toxins, which can cause liver poisoning. Taking Alpha Lipoic Acid (100mg. per day) can help
increase Glutathione levels, and it also works synergistically with Vitamins C, E and Co-Q 10 to provide a
powerful antioxidant defense system against free radical damage.
GLUTATHIONE AND THE IMMUNE SYSTEM
Low levels of Glutathione have been associated with low immune function. Since Glutathione levels reduce
as we age, this has a particular effect on the immune systems of the older population. Glutathione has a role
in T-cell production and function, and stimulates interleucan (IL-1) and (IL-2) which are necessary for the
growth of new immune cells and inflammatory responses to fight against new infections. Lymphocyte
proliferation is increased aiding new immune formation as well.
GLUTATHIONE: DISEASE & AGING
Low levels are found in many ill patients, including those with atherosclerosis, AIDS and cancer. Glutathione
prohibits the activation of the genes that can cause chronic inflammation, which can lead to arthritis and
other serious health problems like Lupis (and other autoimmune diseases). One of the causes of
Parkinsonís disease appears to be dopaminergic neuronal loss. Low Glutathione levels have been noted in
this condition, which might have an effect on the degeneration of these neurons. Since the lung linings
contain Glutathione, necessary to detoxify the toxins we get from smog and other environmental pollutants, it
is important to keep the Glutathione levels high to prevent depletion. Low levels have been noted in those
who suffer from chronic respiratory infections and ailments such as asthma. A recent study (May 2000) of
patients admitted to a hospital with chronic diseases, including cancer, gastrointestinal disorders,
cardiovascular, and muscular-skeletal, noted over 36% had low Glutathione levels.
Glutathione can protect the cells from the damage of carcinogenic free radicals, such as very damaging
hydroxyl radicals, (from hydrogen peroxides). When the cellís DNA is damaged, the cell can mutate and
this can lead to cancer. Glutathione acts to prevent this damage, by keeping the hydrogen peroxides at
a low level. Glutathione also acts to protect the DNA of the cells, by activating cell enzymes, which help
In a study, those infected with HIV virus and AIDS had lower Glutathione levels than the control group. It
is also noted, that Glutathione has an effect on the replication of this virus, while boosting the immune
system. Researches have shown that increasing Glutathione levels significantly increased survival rates
in those studied.
Oxidative stress from free radicals formation appears to have a definite role in creating atherosclerotic
plaques. Low levels of Glutathione are present in human atherosclerotic lesions, caused by an
antioxidant/prooxidant imbalance, as well as high homocysteine levels. Maintaining high levels of
Glutathione, (also combined with other antioxidant supplementation of Vitamin C, E, Co-Q 10, Taurine
and Alpha Lipoic Acid) is very beneficial for a healthy cardiovascular system. Folic acid is also
recommended to prevent and/or reduce homocysteine levels.
Glutathione levels are depleted in the mucosal bowel tissue in acute Colitis. In a recent study, May
2000, evidence was reported, showing that increasing levels of Glutathione in inflammatory bowel
disease attenuated the acute colitis.
Suggested use: Take 1/4th to 1/2ths of a level teaspoon per day or as directed by a health care professional.