To date, medical treatment options for age-related macular degeneration (ARMD) are few. However, clinical nutrition studies since the late 1980s are continuing to mount, signifying a pivotal role for using certain nutrients to not only stave off the progression of AMRD1 but also improve visual outcome and macular pigment optical density (MPOD).
Population-based and case-control studies suggest a protective role of zinc and antioxidants, ingested either as part of one's diet or as a supplement. These studies are supported by the AREDS (age-related eye disease study) trial, which demonstrated a 25% reduction in the development of advanced ARMD in the group taking combined doses of zinc, antioxidants and copper over a six-year period. The Lutein Antioxidant Supplementation Trial (LAST)2 and the oral zinc trial by Newsome also reported a positive effect of nutritional supplementation on ARMD. There is also increasing circumstantial evidence for the beneficial effects from the carotenoids lutein and zeaxanthin, which weren't included in the AREDS supplement.
Higher concentrations of lutein and zeaxanthin result in a thicker MPOD which is associated with lower rates of ARMD. MPOD can also be increased with dietary supplements containing higher dosages of lutein as well as bilberry extract. Earlier studies suggest that approximately 6mg of lutein are necessary to decrease the risk of ARMD, yet, the Veterans LAST study showed visual function improvement and thicker MPOD in patients with severe ARMD using 10 mg of lutein along with a broad spectrum formula of antioxidants and other supporting vitamins and minerals.
In contrast with the AREDS trial, which used isolated beta carotene as its only carotenoid, the LAST study used mixed carotenoids, which may explain improvements in the visual outcome2 when compared to the AREDS study. Similar to the Veterans LAST study, Vital Eyes® Complete contains only mixed carotenoids. In the AREDS trial as well as other studies, isolated beta carotene has been shown to compete with supplemental and/or dietary sources of lutein. Additional forthcoming studies will continue to examine supplemental lutein while measuring changes in MPOD, blood levels, macular function and the development of ARMD.
Vital Eyes® Complete is a broad spectrum antioxidant formula with the ocular-specific nutrients such as Lutein, Zeaxanthin, Bilberry and Taurine.
Serving Size: 2 capsules
Servings Per Container: 30
Vitamin A (as Betatene mixed carotenoids) 18,000 iu
Vitamin C (as Ascorbic Acid and Ascorbyl Palmitate) 500 mg.
Vitamin D (as cholecalciferol) 400 IU
Vitamin E - natural (as d-alpha tocopheryl acid succinate) 200 iu
Vitamin K 100 mcg
Thiamine (as thiamine mononitrate) 10 mg
Riboflavin 15 mg
Niacin (as niacinamide) 25 mg
Vitamin B-6 (as Pyridoxine HCl) 15 mg
Folate (as folic acid) 400 mcg
Vitamin B-12 (as cyanocobalamin) 100 mcg
Biotin 300 mcg
Pantothenic Acid 25 mg
Zinc (as Zinc Picolinate) 60 mg
Selenium (as L-Selenomethionine) 200 mcg.
Copper (as Copper Citrate) 2 mg
Manganese (as Manganese Aspartate) 10 mg
Chromium (as Chromium picolinate) 200 mcg
Molybdenum (as sodium molybdate) 25 mcg
Taurine 100 mg
Lemon Bioflavonoids (includes 200 Rutin) 500 mg.
Lipoic Acid 100 mg
Bilberry Fruit Extract 50 mg
(vaccinium myrtillus. standardized to 25% anthocynaosides)
Co-Enzyme Q10 30 mg
Lutein 10 mg
Zeaxanthin 5 mg
Other ingredients: Vegetarian cellulose capsule.
Preservative and Excipient-free