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Vitamin E is a vitamin which is involved in maintaining the integrity, function, and flexibility of cell membranes. It stabilizes the cell membrane, which is a necessary feature for ensuring cell health. Vitamin E also serves an important antioxidant function in the body, which means that it prevents harmful substances, called free radicals, from attacking and damaging the cell membrane.
Vitamin E and Female Concerns
Vitamin E regulates prostaglandin production (hormone-like substances which can cause inflammation and muscle cramping) and can alleviate menstrual cramps (Eaton, John MD. Vitamin E use in Neurology. The Western Journal of Medicine, May 1989;150(5). Vitamin E is reported to alleviate many of the symptoms of menopause, from vaginal dryness and hot flashes, to breast tenderness and nervousness. "Vitamin E is a hormone normalizer... appears to have a stabilizing effect on estrogen levels, increasing the hormone output in women who are deficient and lowering it in those who are prone to excess" (Ojeda, Linda, PhD. Menopause without Medicine. Hunter House Publ., Alameda Ca. 1989). Dr. M. Werbach, MD, cites several trials from the 40's and early 50's, which found that vitamin E given in doses of between 20 and 100 mg from one week to several months reduced the circulation symptoms (such as hot flashes) and other menopausal complaints of most of the women being treated (Werbach, MR, MD. Nutritional influences on illness: menopausal symptoms. Int J of Alt & Comp Med, July 1994;19). Improvement included the appearance of new blood vessels in the vaginal wall. In one of the studies, symptoms reocurred when vitamin E supplementation was stopped.
Vitamin E and Heart Disease
When the red blood cell membrane is oxidized, it loses its ability to change shape and squeeze through the vessels, and leads to a rupturing of the membrane, or hemolysis. Vitamin E has demonstrated a protective effect against this hemolysis in blood diseases, including sickle cell anemia. "In these diseases, there is extra oxidant stress, or a decrease in other protective mechanisms, so that the effects of Vitamin E are more readily seen" (Halliwell and Gutteridge, Free Radicals in Biology and Medicine, 1990. New York, Oxford University Press, p. 173).
Vitamin E and the Immune System
Vitamin E protects cells, including the cells of the immune system. Additionally, it seems to boost immune activity. "Vitamins E, A, C and carotenoids are able to protect cells and enhance humoral and cellular immune responses in disease" (Nockels, C.F. The role of vitamins in modulating disease resistance. 1988. Vet Clin North Am Food Anim Pract 4(3):531-42). When the cell's balance is disrupted, hormone receptors are inactivated, and DNA is damaged by free radical attack. It is easy to see how radicals are associated with such degenerative diseases as cancer, diabetes, hypertension and heart disease. Indeed, "Several inherited progressive diseases of the central nervous system may be due to lipid peroxidation" (Ames, B.N. Science 221:1261). Lipid peroxidation is a damaging chain reaction of destruction caused by free radicals which have not been stopped by antioxidants such as vitamin E.
Principal uses include: antioxidant (protects cells from damaging free radicals), inhibits coagulation (blood clotting), strengthens capillary walls, stabilizes cell membranes, prevents proteins, lipids, hormones (such as pituitary and adrenal), and other substances from being oxidized; useful in all diseases either caused by free radical damage or resulting in free radical damage (especially diabetes and eye disorders), skin conditions, menopause, restless leg syndrome, and heart disease.
Vitamin E and Glucose Control
The president of the American Diabetes Association has noted that supplementation of diabetic patients with vitamins E and C can reduce the disease symptoms. It is thought that the ability of vitamin E to stabilize the cell membrane and protect the flexibility helps the mobilization and utilization of the insulin receptors. When the insulin receptors function properly, they can bring glucose into the cells from the blood, thereby lowering blood glucose. In an issue of the American Journal of Clinical Nutrition (June, 1994), twenty elderly subjects were studied for glucose control. Those receiving 900 mg of vitamin E for four months had their glucose disposal "significantly potentiated", and the authors concluded that plasma vitamin E concentrations seem to play an important role in regulating insulin action in elderly people. They also said that daily oral vitamin E supplements might improve the integrity of plasma membranes and their related activities of transporting glucose (AJCN, June, 1994, p. 1295).
The recommended dosage of vitamin E is approximately 400 IU/day. This is high enough to obtain benefits, without risk of overdoing the anti-platelet effect, or of interfering with the function of the gamma tocopherols.
Since vitamin E reduces blood clotting, which is considered to be a favorable effect in reducing risk for heart disease, it should not be combined with anticoagulant drugs. Although caution is advised when taking vitamin E with other herbs containing anti-platelet activity, it is not necessarily contraindicated. For instance, ginkgo biloba and vitamin E can be safely combined. Certain factors, such as individual concerns, and amount of the supplement, need to be taken into consideration. A trained health professional should be consulted to help make an informed decision. Therapeutic amounts of any nutrient should always be taken with the advice of a trained professional.
Disclaimer: The statements above have not been evaluated by the FDA. The nutritional suggestions and research provided are for informational purposes only and are not intended to diagnose, treat, cure or prevent disease and should not be used as a substitute for sound medical advice. Please see your health care professional in all matters pertaining to your physical health.
E Succinate is an anti-oxidant affecting lipid metabolism and fatty cell walls. It maintains platelet aggregation levels that are already within the normal range, and maintains healthy cardiovascular and lung function.
SERVING SIZE:1 Vcap/SERVINGS PER CONTAINER:100
AMOUNT PER SERVING: %DV
Vitamin E(Natural)................400 IU 1332 (d-alpha tocopheryl succinate)
Cellulose Powder, Silica.
Free of coatings, binders, fillers, dairy, wheat, eggs, soy, yeast, corn, sugar, starch, preservatives or hydrogenated oil.
Take 1 capsule once or twice daily with food or as directed by your healthcare professional.
WARNING: If pregnant, consult your physician before taking this or any other product.