Two different methods can be used for the production of coenzyme Q10. One method is natural and the other is synthetic. The natural process utilizes living organisms and is referred to as a “biological fermentation/extraction process.” Coenzyme Q10 can also be synthesized by a chemical process, which produces a similar, but distinctly different product that contains chemical compounds not found in the natural form. Vitaline Chewable CoQ10 contains the natural form of coenzyme Q10.
Vitaline Chewable CoQ10 is a dietary supplement to enhance cellular mitochondrial levels of CoQ10, with subsequent support of CoQ10 affected physical systems, including support of cardiac, neurological, and immune health.
Vitaline Chewable CoQ10 is formulated with a proprietary process that enhances the absorption of CoQ10.
How Does It Work?
CoQ10, also referred to as coenzyme Q 10 or ubiquinone, is a natural fat-soluble nutrient present in virtually all living cells in the body. CoQ10 has a crucial role as a cofactor in the mitochondrial synthesis of cellular energy. Although it is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body's requirement. A deficiency can result from impaired synthesis due to nutritional deficiencies, increasing age, or increased tissue demands. Numerous diseases may exhibit CoQ10 depletion. CoQ10 also functions as a potent antioxidant.
However, all CoQ10 products are not equal. They vary greatly in quality and absorbability. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy.4 In order for it to be fully effective, it must cross the cellular barrier and raise the intracellular levels. The only reliable indicator of CoQ10 supplementation is its presence in cell mitochondria. In central nervous system applications, CoQ10 must pass the blood brain barrier, resulting in increased brain intracellular levels to exert its effects.
Vitaline Chewable CoQ10 is supported by studies that show increased serum levels, increased intracellular levels, and demonstrated ability to cross the blood brain barrier.
Mitochondria are highly specialized structures (organelles) within each nucleated cell. The number of mitochondria in a cell depends on the cell's function. Cells with particularly heavy energy demands, such as heart muscle cells, have more mitochondria than other cells. The mitochondria's primary responsibility is to capture most of the energy in nutrients and convert it into cellular energy. This energy conversion and storage is a complex, multi-step process that follows a specific pathway.
The converted cellular energy is stored in the energy-yielding molecule adenosine triphosphate (ATP) used to fuel the cell's activities. (This is similar to the energy stored in gasoline that is used to fuel automobiles). Because this process requires oxygen, it is often referred to as cellular respiration. Obtaining as many electrons out of the nutrients as possible is the goal of cellular respiration. That is why part of the pathway is referred to as the electron pathway chain. CoQ10 functions as a vital link in the process of converting nutrients into ATP. Cellular respiration and the electron transport chain are completely dependent on CoQ10.
Mitochondria are encased in double membranes. The smooth outer membrane encloses the periphery of the mitochondria and the inner membrane is enfolded to form the cristae. CoQ10 is found in the cristae folds. Cristae folds provide a large surface area for cellular respiration.
Mitochondria are unusual organelles in that they contain their own deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Insufficient CoQ10 levels may have an effect on cellular respiration and mitochondrial DNA.
Vitaline, Chewable CoQ10, and Support of Cardiac Health
Cardiac cells require large amounts of uninterrupted energy. They have a greater number of mitochondria and subsequently more CoQ10 than any other type of cell. Because of this association, CoQ10's support of cardiac health is well researched and documented. CoQ10 supports healthy heart contractility and subsequent circulation, blood pressure, and exercise endurance. Due to Vitaline Chewable CoQ10's ability to pass through the cell membrane and enter the mitochondria, enhanced levels can be attained. Vitaline Chewable CoQ10 and Support of the Neurological System
The Blood-Brain Barrier
The blood-barrier is a unique anatomical structure. Simply stated, the cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can and cannot leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain from potentially toxic substances, it can be a significant obstacle to therapy of central nervous system disorders. In order to leave the bloodstream and reach the brain cells, a substance must be able to pass through the tightly connected cells of the capillary walls. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.
Recently, CoQ10 has been studied for its effect in support of neurological health. When CoQ10 crosses the blood-brain barrier, mitochondrial concentrations are increased and clinical results indicate that significant neurosupportive effects follow. Clinical studies have examined the role of CoQ10 in the neurological system.
Vitaline Chewable CoQ10 and Support of Immune Health
CoQ10 is necessary for immune health. Increased free radical activity causes damage to cell membranes, mitochondria, and DNA. Supplementation with CoQ10 provides enhanced antioxidant activity that is supportive of the immune system.
Vitaline Chewable CoQ10's Ability to Enter Mitochondria and Cross the Blood-Brain Barrier
CoQ10 is a large, fat-soluble molecule. When CoQ10 is manufactured with Micosolle®, it allows the molecule to change shape and become more flexible. The CoQ10 can then enter the cellular mitochondria and cross the blood-brain barrier.
Through special processing techniques, Vitaline Chewable CoQ10, may be absorbed by the lymphatic system. This allows the CoQ10 to initially bypass the liver, resulting in increased absorption potential. Vitaline Chewable CoQ10, is supported by published studies that demonstrate ability to cross the blood brain barrier.
Vitaline Chewable CoQ10 and Clinical Trials
The formulation of Vitaline CoQ10 is unique among CoQ10 supplements. Currently, three large multi-center studies investigating Vitaline Chewable CoQ10 are ongoing. All of these clinical trials are investigating Vitaline Chewable CoQ10 health supportive effects on the nervous system. To date, 21 published studies have used Vitaline Chewable CoQ10 in their research.
CoQ10 Maple Nut Flavor 200 mg 400 chew
Serving size 1 wafer
Servings per container 400
Amount per wafer:
Total Carbohydrate 2 g
Vitamin E (as d-alpha tocopheryl acetate) 400 IU
Coenzyme Q10 (CoQ10) (ubiquinone 10) 200 mg
Dextrose, rice maltodextrin, fructose, natural flavors, silicon dioxide, tricalcium phosphate, magnesium sulfate, safflower oil, and soybean oil.
Contains no salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, preservatives, or ingredients of animal origin. This product contains natural ingredients; color variations are normal.
Adults chew 1 wafer once or twice daily or as directed by your healthcare practitioner.
If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use.